                           ˿µϣ20171121գ

17.11.19-20ûи
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17.11.21, FMĿӽѧ196ݸ좻᲻°
17.11.21, Crystalٱٸ˿ƼɼڸǻͺߵõĲϺʵ
17.11.21, ࡶÿѧ¡
17.11.21, ҽƴѧθУѧ˵
17.11.21, ŦԼʱй³
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17.11.21, BBCйܹܡ³Ϊ
17.11.21, غϼ1922017.11.01-05

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кôԻ߾ѡ߸ɴ಻ֲƣ˳ȻһͲ
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2017.5.14

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ٱٸ˿ƼɼڸǻͺߵõĲϺʵ

ߣCrystal

2017917Ϣй֮ȫ޶
йԺԺʿΥѧΪ취շ취ԺʿΥ
ѧµļΪ涨˾ĴʩУԺʿĸΪ漰ɥʧ
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Ժʿѡͬá

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Աںڡ˵ںҲ˾ܾθĿӿ鳤

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ΪʲôΪʲôԽŪԽͿ⡣ԭ£1.
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ԱǲٸģĿ? ʵҲû

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ÿѧ

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ȻЧɹ֮һͨͳƽɵά
ʱĿѧҸ˹߶٣Francis Golton1872
飺һЧϵӦ٣ӢȻӢ
ʼҳԱࣻͬһصĲֲͬǷ
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굽һ֪ģֻṩ˱༭ߺ͸
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ҪӿѧǶƷϵ񼣵˵ÿѧķٴĽ
׼飬ںղءɭ2006STEPо
A study of the Therapeutic Effects of Intercessory Prayer
ЧоΪоܵڿѧڽ̶ԻԼջ
֧֣Ҳ㷺Ϊջо6ҽԺ1,800
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ʵһһȷ֪Ϊ
Ҳȷʵ˽רְԱ䷽ʽʩУ
ΪϵȷʲôбȷĿĺ;Ĳ֣硰
˳ٻָ޲֢ȵȡ

սǣǰ鲻ԤϵûԲ࣬ƺĶԵ
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ǰϷԣ¡˹д
ϵ˼the God Delusion档

ٴԽ©ٳ飬Խ
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ˣŶЩϵͽκӰ죬ΪܾѧԶԴԵ
ǲġй˶ҽҲơ

ôءӺͲͿѧԱԵ
ɿЦˣݸߵѣⲻ˱ѧѹ

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ҽƴѧθУѧ˵

˵ιʾӣ
http://www.nxnews.net/sz/gbgs/201711/t20171109_4410737.html

ΪĵΨһһҽѧУεѡȻ֤ȷ
ѧΪԽˣѧ˵鿴ĵ
ĵеҽѧԺ20089ʽΪҽƴѧ

ҽѧԺJiang Yideng٣2008ͶJournal of Experimental 
Biology (JEB)ϵѱ壬ƪҲб½ɣ
־ҽѧԺ۲ÿɷɼӰ졣ɣ

The Journal of Experimental Biology (JEB) has issued the first 
retraction in its 85 year history, the journal reported in an 
editorial and a retraction notice in its December 1 issue. Although 
the authors' institution told JEB their reuse of images was a careless 
error, the journal's editor-in-chief called it a case of outright fraud. 
Journal of Experimental Biology (JEB)85һι塣
淢12µһСȻڵλ֪Journal of Experimental 
Biology (JEB)¼ͼʧ󣬵ǣ־϶һȻ١

The retracted paper -- published by Yideng Jiang, a molecular 
biologist at Ningxia Medical College in Yinchuan, China, and his 
colleagues in the March 15, 2008 issue of the journal -- investigated 
the effects of the amino acid-like compound homocysteine on the 
accumulation of cholesterol-rich macrophages known as foam cells. 
ϵйҽѧԺJiang Yidengͬ£·־ 
  2008-3-15оeffects of the amino acid-like compound 
homocysteine on the accumulation of cholesterol-rich macrophages known 
as foam cells. 

A reader alerted the journal's editor-in-chief, Hans Hoppeler, a 
physiologist at the University of Bern in Switzerland, that "he had 
seen similar plots in other papers," Hoppeler told The Scientist. "We 
tracked that, and it was quite obvious that the same plot was used in 
several publications." 
һλ־࣬ʿѧѧHans Hoppelerö
пݡ֪λѧң˶ԣͬݱ
ڼƪ¡

Hoppeler hired an independent expert -- "a senior high level 
academic working with the same technology in a very close field, but 
unrelated to [JEB] or that particular area of research" -- who found 
that figure 6B in the paper re-used Western blot bands that had been 
published the previous year in a paper in DNA and Cell Biology. 
HoppelerӶһλרңר뱾־޹ء
鷢֣ͼ6BеWestern blot֮ǰDNA and Cell 
Biology.еһƪʹá

Hoppeler said the re-used Western blots were also likely used in 
at least one other paper, but did not say which. "It depends where you 
set the level of evidence," he noted. 
Hoppelerظʹõͼƺֹһƪг֡

Jiang has published only three other papers, a second paper in DNA 
and Cell Biology this year and two papers in Acta Biochimica et 
Biophysica Sinica in May and September 2007, according to both ISI and 
Pubmed. Of these papers, The Scientist found only one other that 
showed Western blots analyzing similar data to that found in the 
retracted JEB study -- figure 7 of the September 2007 Acta Biochimica 
et Biophysica Sinica paper. 
JiangѾƪ£һƪ2008DNA and Cell Biology
ϣƪ2007º;·Acta Biochimica et Biophysica 
Sinicaϡ߷ַ2008JEB־ϵWestern blots뷢 
2007 Acta Biochimica et Biophysica Sinica ϵͼ7һ¡

JEB -- a journal with a 2007 impact factor of 2.97 according to 
ISI -- also concluded that the paper contained discrepancies in the 
methods and materials section, and that other data were mislabeled or 
inappropriately presented. 
JEB־ͬʱóۣڷϴìܣ
Ǵʹò⡣
At JEB's request, Ningxia Medical College -- the institute of six 
of the paper's seven authors -- carried out its own investigation, 
which concluded that the authors mistakenly reused the Western blot 
images due to carelessness in computer file-naming, and that further 
inaccuracies stemmed from limited English abilities, according to the 
published retraction. 
JEB־ҪλеλλҽѧԺ˵
顣Ϊ߼ļʧ´ظʹͼ
Ӣ¡
Jiang and his coworkers confirmed the error in figure 6B and 
provided a revised image to JEB. They did not admit any other problems 
with the paper, said Hoppeler, who has served on JEB's editorial board 
since 1995 and as editor-in-chief since 2004. 
Hoppeler ΪJEB ־鹤13꣬2004ࡣ˵:
Jiangȷͼ6BĴ󣬲ṩһ޸ĺͼJEB
ǲûгϳе⡣
JEB also contacted the West China College of Preclinical and 
Forensic Medical Sciences at Sichuan University, the institute of the 
paper's last author, Shuren Wang, but never received acknowledgement 
of any of their letters or E-mails. 
JEB־ϵһλShuren WangڵλĴѧҽѧ
Ժûܵκλš
"I think this was fraud," Hoppeler told The Scientist. But a 
retraction is "as far as we can go. We have the retraction, we know 
the facts are on the table, and it's clear to anybody who will ever 
read the paper [that this was fraud]. Beyond that it's not [JEB's] 
responsibility to go any further." 
Hoppeler˵ΪһƭΪֻǳ塣
Ѿ塣֪ʵѰϣκֻҪ¶һĿ
ȻһΪ
DNA and Cell Biology has been alerted of the problem, but no 
further actions have been taken, Hoppeler said. 
һ־DNA and Cell BiologyҲѾ֪¼ǻδȡж
Jiang's 2007 DNA and Cell Biology paper has been cited 5 times 
according to ISI. Jiang's retracted JEB paper has not been cited. 
Jiang2007귢DNA and Cell Biologyϵѱ5Ρ
δá
JEB's publisher, the Company of Biologists, declined to comment 
for this article. Jiang did not respond to E-mail requests for an 
interview.
ۣ

Return to Top
comment:
When in doubt, ask to see raw data before approving a paper to be 
published
by anonymous poster

[Comment posted 2008-11-30 10:01:43]
I think beside the obvious responsibility of the authors for such 
scandalous misconduct, reviewers and editors overseeing such obvious 
attempts to betray the scientific community have to be blamed too. 
Proper peer review needs time! 

XXXXXXXXXXX 

This is just the tip of the iceberg when it comes to how much 
non-sense papers get published even in many highly visible journals. I 
think the public must be made aware of on how their tax money is being 
used in the name of Biological Science research. We should draw 
attention of The senators and Congressmen to these issues. It's high 
time. 

One way to counteract this is: 

The Reviewers and Editors should be held accountable as the authors, 
when a published paper is revealed to be fraudulent. 

Their names should be revealed for everyone to see - so they can 
be judged by their ethical lapses as the corrupted authors. 

While reviewing an article for a journal, he Reviewers/Editors 
should have the rights to ask for RAW data/DNA constructs/details of 
the sources, screening data on antibodies or transgenics that have 
been made to be used in the studies, etc, should there be a need. 

Implement this, and you will see, there will be a very FEW people 
left to continue in the profession of Biological Research, there will 
be LESS publications. But then there will be only honest ones left and 
quality research done.

________________________________________

Return to Top
comment:
More retractions expected
Ӧÿ೷
by anonymous poster

[Comment posted 2008-11-21 04:53:57]
Thank you to The Scientist for commenting on this retraction. The 
authors in question have published six relevant papers. Cursory and 
detailed examination will reward the careful observer with many more 
examples of "unscientific file-naming conventions and negligence". One 
of the more creative involves Fig 6 from 1., Fig 5b from 3. and Fig 3b 
from 5. I await, with hopeful interest, the retraction from DNA Cell 
Biology, who were informed of these irregularities on 6 March 2008. 

1. Yideng Jiang, Zhihong L, Jiantuan X, Jun C, Guizhong L, Shuren 
Wang. Homocysteine-mediated PPARalpha,gamma DNA methylation and its 
potential pathogenic mechanism in monocytes. DNA Cell Biol. 
2008;27(3):143-50. 
2. Jiang Yideng, Jiang J, Xiong J, Cao J, Li N, Li G, Wang Shuren. 
Homocysteine-induced extracellular superoxide dismutase and its 
epigenetic mechanisms in monocytes. J Exp Biol. 2008;211(Pt 6):911-20. 
ѱ

3. Jiang Yideng, Sun T, Xiong J, Cao J, Li G, Wang Shuren. 
Hyperhomocysteinemia-mediated DNA hypomethylation and its potential 
epigenetic role in rats. Acta Biochim Biophys Sin (Shanghai). 
2007;39(9):657-67. 


4. Yi-Deng Jiang, Tao S, Hui-Ping Z, Jian-Tuan X, Jun C, Gui-Zhong 
L, Shu-Ren Wang. Folate and ApoE DNA methylation induced by 
homocysteine in human monocytes. DNA Cell Biol. 2007;26(10):737-44. 


5. Yideng Jiang, Jianzhong Z, Ying H, Juan S, Jinge Z, Shenglan W, 
Xiaoqun H, Shuren Wang. Homocysteine-mediated expression of SAHH, DNMTs, 
MBD2, and DNA hypomethylation potential pathogenic mechanism in VSMCs. 
DNA Cell Biol. 2007;26(8):603-11. 

6. Jiang Yideng, Zhang J, Xiong J, Cao J, Li G, Wang Shuren. 
Ligands of peroxisome proliferator-activated receptor inhibit 
homocysteine-induced DNA methylation of inducible nitric oxide 
synthase gene. Acta Biochim Biophys Sin (Shanghai). 2007;39(5):366-76. 

________________________________________

Return to Top
comment:
Re-used Blots and Figures
by ERIK MARONDE

[Comment posted 2008-11-20 15:22:07]
As a reviewer I made a similar experience with a manuscript from a 
mostly Chinese affiliated author group. Due to serious concerns on the 
correctness of the description of the experiments and the obviously 
reused figures (2 of 5) from an already published paper I rejected the 
manuscript and corresponded my reasons to the editor. Some weeks later 
I received the unchanged manuscript to review for another journal and 
rejected it again once more reporting my reasons. Finally I saw the 
manuscript published, mostly unchanged. Later I had a similar 
experience but before I sent my review the editor decided to reject 
the manuscript due to serious ethical concerns and suspected fraud. I 
think beside the obvious responsibility of the authors for such 
scandalous misconduct, reviewers and editors overseeing such obvious 
attempts to betray the scientific community have to be blamed too. 
Proper peer review needs time!

(XYS20171121)

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ձ2017 11 22

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غϼ1922017.11.01-05

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ոԤ˾϶ûλϴԵʿ˺ܴۣΪ
7λֱȴķ棬Ұ°11ֲӽ
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ʿӵTalibanġмΪӪȷʵе
֡зеʹնŸɵ˼ߡҪ

?Verified account 
@fangshimin
Nov 4
  Retweeted Peter Z
˵Ӿ͸˵ӣطû˵ӡʿΪӪ˵ģ
ûģǴҥͳԤ˾˾ֱ
طߣԶֻܼ߳ͥǳʶѧ
֪ʶٷۡ

EmiyaGuang? 
@EmiyaGuang

Replying to @fangshimin
´δֻҪ˵һܵõǵĹִ᳹

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@fangshimin
Nov 4
  Retweeted EmiyaGuang
·ͥķٶ˰ЩξвյĶǰ

jimiwong? 
@hellosweet77888

Replying to @fangshimin
ٿԲͳĹңΪʲôͳ߼Ϊĺ֮ȣ??

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Nov 4
  Retweeted jimiwong
ڽͳٶܲˣȻû䡣

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@fangshimin
Nov 3

ɹŴ뵽ǲԭɳĮƣйĴɳĮ
ռȥнСڸɳĮɹŵһˡ
൱طĵؼС˸ڵذسһصָͣ
Ʒûǲ֢˵Ǹ
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El Manu? 
@sunxiaokang_als

Replying to @fangshimin
̲裬 Ƥ еӣ룩嵰ӣ룩һǲ
Сףӭʦǰƣ

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@fangshimin
Nov 4
  Retweeted El Manu
2008ȥģ˽ʲôˡ

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@fangshimin
Nov 4

ڸй˵ġʮǰҥԣžó˵
˭أҲ˵ǲŴѧ˵ĺ˼룬վס
ʮǰҾҪĻô໪ˡйѧй
ͣ»õйɼ
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https://pbs.twimg.com/media/DNxZa8dU8AAsoFJ.jpg

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@fangshimin
Nov 4

ҼֵĶֲ152
https://pbs.twimg.com/media/DN1DF63UEAAF82-.jpg

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@fangshimin
Nov 4

ŮԼһޱȸӵĿϷ
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https://pbs.twimg.com/media/DN1JjyiVAAAnGfp.jpg

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@fangshimin
Nov 4

ƾ˵ǺɽгںɽȱɹŰظŵ
ֳ衣Ⱦƣ裬ڸߴɹŰա
https://pbs.twimg.com/media/DN1YOI0V4AAC7Ir.jpg
https://pbs.twimg.com/media/DN1YPYyUMAAjgzw.jpg
https://pbs.twimg.com/media/DN1YQ9oVoAACyxs.jpg
https://pbs.twimg.com/media/DN1YS3UVAAEOfKh.jpg

Yaming Wang? 
@wangyamingc1

Replying to @fangshimin
Ϸɶƹ

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Nov 4
  Retweeted Yaming Wang
ҿ˺Ⱦ

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@fangshimin
Nov 4

£ҩϴð
http://mp.weixin.qq.com/s/ANT-uYbR9VPruSk44MHmXg 

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@fangshimin
Nov 4

˵δ뱻ϺѺͱ;вûԲţӶݣ䰢ƺ
ܶꡣƹԭ50ǰջ٣90ǻҡ
ʷ֤Ĵ˵ʫи֡ǶУ ɽ
ֱֿǣ䰲˫ȫ 䡣
https://pbs.twimg.com/media/DN13Ne3UIAA1v1h.jpg
https://pbs.twimg.com/media/DN13O51UIAAJIpu.jpg
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https://pbs.twimg.com/media/DN13SqKVAAE8B06.jpg

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@fangshimin
Nov 4

ѧӢ³ġ󹲺͵ˡһУϲʲ˵һblowhard
ʺ˼ţƤͶƱϣСʲ˵ղ֪ô
ͳ˭ͶûͶϣΪʼ¼ϣж
⣬簲ȫ
https://pbs.twimg.com/media/DN2Rj6_UEAAf17G.jpg
https://pbs.twimg.com/media/DN2Rj6_U8AAPXo8.jpg
https://pbs.twimg.com/media/DN2Rj7HUMAAYJFi.jpg

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@fangshimin
Nov 4

˴۹ںҥ˵ᷢȫ󱩶ִ˺
йѧһҪСģŵúܶന۶ﲻҳ˰ɣֻЩط
˿鴨յĺƽʾƽ˾عȥˡùںֻٴҥ
Ż۵ġ
https://pbs.twimg.com/media/DN2Z8sDUMAE4ZRH.jpg
https://pbs.twimg.com/media/DN2Z8sJUEAAApnK.jpg
https://pbs.twimg.com/media/DN2Z8sAVQAABYgP.jpg
https://pbs.twimg.com/media/DN2Z8sGU8AAeIFk.jpg

?Verified account 
@fangshimin
Nov 5

ſڿܻ𳵣ҽҽ۲û𡣻βûбھ
ҰĻеǣûΪΣֲֲεĶ
ô󱾵ˣ̨ˣȻҪޡûк
ǰǴй̫ƽɱĺƤëǺޡ
https://pbs.twimg.com/media/DN2mAe2UIAAZ-8B.jpg

?Verified account 
@fangshimin
Nov 5

ҼֵĶֲ153
https://pbs.twimg.com/media/DN6UEejV4AAKOsj.jpg

?Verified account 
@fangshimin
Nov 5

ÿ˹һСĽðԶǹɱ26ݵĽͽС
ǰڿվڣڻѧУ幤Сҳ
.µĻҲҳ֮ǰ꣬û
е˿Ĳ㡣Ĭ˵ˣ
https://pbs.twimg.com/media/DN6ZaUBVwAAV6Ho.jpg

?Verified account 
@fangshimin
Nov 5

ɪȪòҰ󣬴շ˵ԸϵɪȪͬڣ
ݳ˵ϵ۵οָԱ׷ױʾҪ
ΪЩȥݵȥģȥȥģ֮ڲԮ
֣֮տ˵׻ȡжǹ
https://pbs.twimg.com/media/DN6h9NJVoAE73Xt.jpg
https://pbs.twimg.com/media/DN6h9NHU8AAxXZK.jpg
https://pbs.twimg.com/media/DN6h9NHUIAAzyRJ.jpg

Michael һ? 
@Michaelrealgao

Replying to @fangshimin
йûǹ㿴ʲôˡ

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@fangshimin
Nov 5
  Retweeted Michael һ
ô񡢰ĴŷҲûǹɶˣ

 ????? 
@laosan

Replying to @fangshimin
ô󡢰Ĵ˽˳ǹ

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@fangshimin
Nov 5
  Retweeted  ????
ǹڽǹô󡢰Ĵǿǹ֮Чǳԡ

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@fangshimin
Nov 5

＾еhttp://mp.weixin.qq.com/s/OmOOGjme8AWxji2a-MYX-A 

?Verified account 
@fangshimin
Nov 5

ꡰˣĳءïȢ
Ŀڿ⽨ۡﻹ츮֡峯ʱɽ
츮ַˡɽ¸ʻݡйصϷ¥ӹ¥ڳ
ݡ
https://pbs.twimg.com/media/DN67Yc7VAAAFWMO.jpg
https://pbs.twimg.com/media/DN67Z2iVQAAKOtu.jpg
https://pbs.twimg.com/media/DN67bHdUQAAXJ7L.jpg
https://pbs.twimg.com/media/DN67cTUVoAUJvYd.jpg

Peng Liu? 
@apengliu

Replying to @fangshimin
Ϊɶأ

?Verified account 
@fangshimin
Nov 5
  Retweeted Peng Liu
Ϊֻдҵķѧ۲Ż᲻ʱ򶼻ֻ
Ҫ

?Verified account 
@fangshimin
Nov 5

ʷǣֻܿ峯͵½ļٹŶϵĽ
ڵص¡Գɹ򿪷ʱٱ򿪻ƺӵ̰ˣ
Ҳ峯ַһͤӣݱڵͤûʲô
ͷͤ԰һһȵľջչǳʢֵһⱻΪճǡ
https://pbs.twimg.com/media/DN7PasnVAAAbo1t.jpg
https://pbs.twimg.com/media/DN7PgNRVwAAWvVp.jpg
https://pbs.twimg.com/media/DN7PhWoVoAAm7Xl.jpg
https://pbs.twimg.com/media/DN7PidKU8AEWO0F.jpg

alexander? 
@sunweiqiang8

Replying to @fangshimin
ֻ֪Ϻ԰

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@fangshimin
Nov 5
  Retweeted alexander
ЩǷ½ļٹŶƭο͵ġ

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@fangshimin
Nov 5

̡ѧרҵıҵҵʣֻ
ѧҵԴڹ
https://pbs.twimg.com/media/DN7nFkMUMAAsq8x.jpg

?Verified account 
@fangshimin
Nov 5

ǰᵽһֻ20˵ϳɵʣĵ
ĵڿһߵоһֻ30˵ʡ
ԴΪ׼ش˸30˵൱һһţеĶﵰʡ
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https://pbs.twimg.com/media/DN7yG6gUQAAYfKH.jpg

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